For research use only. Not for therapeutic Use.
Aftin-4(CAT: I020264) emerges as a significant compound in the realm of pharmaceutical and neurodegenerative research. Functioning as an Amyloid-β42 (Aβ42) inducer, Aftin-4 holds promise for elucidating mechanisms associated with Alzheimer’s disease and related amyloidopathies. Its selective and potent ability to increase Aβ1-42 levels in various neuronal systems, including N2a cells, primary neurons, and brain lysates, positions it as a valuable tool for studying amyloidosis and exploring potential therapeutic interventions.
| Catalog Number | I020264 |
| CAS Number | 866893-90-5 |
| Molecular Formula | C₂₀H₂₈N₆O |
| Purity | ≥95% |
| Reference | [1]. Meunier J, et al. Brain toxicity and inflammation induced in vivo in mice by the amyloid-β forty-two inducer aftin-4, a roscovitine derivative. J Alzheimers Dis. 2015;44(2):507-24. |
