Afurolol hydrochloride, (R)-

• CAT Number: I021489
• CAS Number: 91853-76-8
• Molecular Formula: C15H22ClNO4
• Molecular Weight: 315.79
• Purity: 98%
• Synonyms: (R)-Afurolol hydrochloride, Afurolol hydrochloride, (R)-
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 1(3H)-Isobenzofuranone, 7-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-, hydrochloride, (R)-
• InChI: 1S/C15H21NO4.ClH/c1-15(2,3)16-7-11(17)9-19-12-6-4-5-10-8-20-14(18)13(10)12;/h4-6,11,16-17H,7-9H2,1-3H3;1H/t11-;/m1./s1
• InChIKey: KTIQCDLYPPAYBF-RFVHGSKJSA-N
• SMILES: CC(C)(C)NC[C@H](COc1cccc2c1C(=O)OC2)O.Cl

(R)-Afurolol hydrochloride (Cat No.: I021489) is the active enantiomer of Afurolol, a beta-adrenergic receptor antagonist with selective activity primarily toward β₁-receptors. It is used in cardiovascular research for its ability to reduce heart rate, cardiac output, and blood pressure, making it relevant in studies on hypertension, arrhythmia, and other heart conditions. The (R)-enantiomer offers enhanced receptor selectivity and potency compared to the racemic mixture. Its defined stereochemistry makes it valuable for examining stereoselective drug-receptor interactions and optimizing beta-blocker pharmacology.