AG 825

• CAT Number: M091184
• CAS Number: 149092-50-2
• Molecular Formula: C19H15N3O3S2
• Molecular Weight: 397.47
• Purity: ≥95%
• Synonyms: (E)-3-(3-((benzo[d]thiazol-2-ylthio)methyl)-4-hydroxy-5-methoxyphenyl)-2-cyanoacrylamide
• Target: Protein Tyrosine Kinase/RTK
• Solubility: Soluble in DMSO > 10 mM
• Storage: Store at +4℃
• IUPAC Name: (E)-3-[3-(1,3-benzothiazol-2-ylsulfanylmethyl)-4-hydroxy-5-methoxyphenyl]-2-cyanoprop-2-enamide
• InChI: 1S/C19H15N3O3S2/c1-25-15-8-11(6-12(9-20)18(21)24)7-13(17(15)23)10-26-19-22-14-4-2-3-5-16(14)27-19/h2-8,23H,10H2,1H3,(H2,21,24)/b12-6+
• InChIKey: KXDONFLNGBQLTN-WUXMJOGZSA-N
• SMILES: COC1=CC(=CC(=C1O)CSC2=NC3=CC=CC=C3S2)/C=C(\C#N)/C(=O)N

AG 825 (Cat.No:M091184) is a small molecule inhibitor that targets epidermal growth factor receptor (EGFR) tyrosine kinase activity. It has shown potential in inhibiting cell proliferation and inducing apoptosis in cancer cells, particularly those with EGFR overexpression. AG 825’s mechanism makes it a candidate for further research in anticancer drug development.