AGARIC ACID

For research use only. Not for therapeutic Use.

  • CAT Number: M000303
  • CAS Number: 666-99-9
  • Molecular Formula: C22H40O7
  • Molecular Weight: 416.555
  • Purity: ≥95%
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Agaric acid (Cat.No:M000303) is a natural organic compound found in certain mushrooms. It has been explored for its potential antiviral and antibacterial properties. Agaric acid’s molecular structure and bioactive characteristics make it a subject of interest in pharmaceutical and medicinal research for its potential therapeutic applications.


Catalog Number M000303
CAS Number 666-99-9
Synonyms

3-nonadecanetricarboxylicacid,2-hydroxy-2;agaric;alpha-cetylcitricacid;laricicacid;n-hexadecylcitricacid;2-HYDROXY-1,2,3-NONADECANETRICARBOXYLIC ACID;AGARICIC ACID;AGARIC ACID

Molecular Formula C22H40O7
Purity ≥95%
Target Mitochondrial Metabolism
Storage RT
IUPAC Name 2-hydroxynonadecane-1,2,3-tricarboxylic acid
InChI InChI=1S/C22H40O7/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-18(20(25)26)22(29,21(27)28)17-19(23)24/h18,29H,2-17H2,1H3,(H,23,24)(H,25,26)(H,27,28)
InChIKey HZLCGUXUOFWCCN-UHFFFAOYSA-N
SMILES CCCCCCCCCCCCCCCCC(C(=O)O)C(CC(=O)O)(C(=O)O)O
Reference

1: Garc&iacute;a N, Pav&oacute;n N, Ch&aacute;vez E. The effect of N-ethylmaleimide on permeability transition as induced by carboxyatractyloside, agaric acid, and oleate. Cell Biochem Biophys. 2008;51(2-3):81-7. doi: 10.1007/s12013-008-9016-5. Epub 2008 Jul 23. PubMed PMID: 18649145.<br />
2: Garc&iacute;a N, Zazueta C, Pav&oacute;n N, Ch&aacute;vez E. Agaric acid induces mitochondrial permeability transition through its interaction with the adenine nucleotide translocase. Its dependence on membrane fluidity. Mitochondrion. 2005 Aug;5(4):272-81. PubMed PMID: 16050990.<br />
3: Freedland RA, Newton RS. Agaric acid. Methods Enzymol. 1981;72:497-506. PubMed PMID: 7311847.<br />
4: Ch&aacute;vez E, Ch&aacute;vez R, Carrasco N. The effect of agaric acid on citrate transport in rat liver mitochondria. Life Sci. 1978 Oct 9;23(14):1423-9. PubMed PMID: 713700.<br />
5: Stipani I, Francia F, Palmieri F, Quagliariello E. [Inhibition by agaric acid of citrate transport in mitochondria]. Boll Soc Ital Biol Sper. 1976 Jun 15;52(11):812-8. Italian. PubMed PMID: 1016634.<br />
6: Ch&aacute;vez E, Klapp M. A new inhibitor of adenine nucleotide translocase in mitochondria: agaric acid. Biochem Biophys Res Commun. 1975 Nov 3;67(1):272-8. PubMed PMID: 128359.<br />
7: Carminati GM, Spina G. [Pharmacological properties of agaric acid]. Boll Chim Farm. 1968 Apr;107(4):249-51. Italian. PubMed PMID: 5721536.<br />
8:<span style=”color: rgb(32, 33, 34); font-family: sans-serif; font-size: 12.6px; font-variant-ligatures: normal; orphans: 2; widows: 2;”>Garc&iacute;a, Noem&iacute;; Zazueta, Cecilia; Pav&oacute;n, Natalia; Ch&aacute;vez, Edmundo (2005). &quot;Agaric acid induces mitochondrial permeability transition through its interaction with the adenine nucleotide translocase. Its dependence on membrane fluidity&quot;.&nbsp;</span><i style=”color: rgb(32, 33, 34); font-family: sans-serif; font-size: 12.6px; font-variant-ligatures: normal; orphans: 2; widows: 2;”>Mitochondrion</i><span style=”color: rgb(32, 33, 34); font-family: sans-serif; font-size: 12.6px; font-variant-ligatures: normal; orphans: 2; widows: 2;”>.&nbsp;</span><b style=”color: rgb(32, 33, 34); font-family: sans-serif; font-size: 12.6px; font-variant-ligatures: normal; orphans: 2; widows: 2;”>5</b><span style=”color: rgb(32, 33, 34); font-family: sans-serif; font-size: 12.6px; font-variant-ligatures: normal; orphans: 2; widows: 2;”>&nbsp;(4): 272&ndash;81.</span>

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