Agatolimod sodium

• CAT Number: I042289
• CAS Number: 541547-35-7
• Molecular Weight: 8204.00
• Purity: ≥95%

Agatolimod sodium (ODN 2006) is a class B CpG ODN and is a TLR9 agonist. Agatolimod sodium can be used as vaccine adjuvant. Agatolimod sodium can be used for the research of cancer. Sequence: 5’-TCGTCGTTTTGTCGTTTTGTCGTT-3’[1][2].
Agatolimod sodium (ODN 2006) (10 μg/mL; 24 and 48 h) increases radiation sensitivity of radiation-resistant human lung adenocarcinoma cell line by overexpression of TLR9[1].

Reference

[1]. Yan L, et al. CpG-ODN 7909 increases radiation sensitivity of radiation-resistant human lung adenocarcinoma cell line by overexpression of Toll-like receptor 9. Cancer Biother Radiopharm. 2013 Sep;28(7):559-64.
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[2]. Cooper CL, et al. Safety and immunogenicity of CPG 7909 injection as an adjuvant to Fluarix influenza vaccine. Vaccine. 2004 Aug 13;22(23-24):3136-43.
 [Content Brief]