AICA-riboside, 5′-phosphate

• CAT Number: R001568
• CAS Number: 3031-94-5
• Molecular Formula: C9H15N4O8P
• Molecular Weight: 338.21
• Purity: ≥95%
• Synonyms: [(2R,3R,5R)-5-(5-amino-4-carbamoylimidazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
• IUPAC Name: [(2R,3S,4R,5R)-5-(5-amino-4-carbamoylimidazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
• InChI: InChI=1S/C9H15N4O8P/c10-7-4(8(11)16)12-2-13(7)9-6(15)5(14)3(21-9)1-20-22(17,18)19/h2-3,5-6,9,14-15H,1,10H2,(H2,11,16)(H2,17,18,19)/t3-,5-,6-,9-/m1/s1
• InChIKey: NOTGFIUVDGNKRI-UUOKFMHZSA-N
• SMILES: C1=NC(=C(N1[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O)N)C(=O)N

AICA-riboside, 5′-phosphate（Cat No.:R001568）is a nucleotide derivative of AICA (5-aminoimidazole-4-carboxamide ribonucleotide), which is involved in the regulation of cellular energy metabolism. As a precursor in the biosynthesis of inosine monophosphate (IMP), it plays a role in purine nucleotide metabolism. This compound is known for its potential to activate AMP-activated protein kinase (AMPK), a key regulator of energy homeostasis. Due to its ability to modulate metabolic processes, AICA-riboside, 5′-phosphate is being explored for its therapeutic potential in treating conditions related to metabolic disorders, diabetes, and obesity.