For research use only. Not for therapeutic Use.
AJH-836(CAT: I021651) is a selective and potent protein kinase C (PKC) activator, specifically targeting the PKCα and PKCβ isoforms. PKC enzymes play critical roles in regulating various cellular processes, including cell proliferation, differentiation, apoptosis, and signal transduction. By activating these PKC isoforms, AJH-836 influences pathways involved in cancer progression, immune responses, and neurodegenerative diseases. Its high selectivity allows for precise modulation of PKC activity, making it a valuable tool in oncology and signal transduction research to explore therapeutic strategies targeting PKC-related pathways.
| Catalog Number | I021651 |
| Synonyms | AJH836; AJH 836; AJH-836; |
| Molecular Formula | C22H38O5 |
| Purity | 98% |
| Solubility | To be determined |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | (E)-(2-(hydroxymethyl)-4-(3-isobutyl-5-methylhexylidene)-5-oxotetrahydrofuran-2-yl)methyl pivalate |
| InChI | InChI=1S/C22H38O5/c1-15(2)10-17(11-16(3)4)8-9-18-12-22(13-23,27-19(18)24)14-26-20(25)21(5,6)7/h9,15-17,23H,8,10-14H2,1-7H3/b18-9+ |
| InChIKey | XKEOGEXDEKIDNA-GIJQJNRQSA-N |
| SMILES | CC(C)(C)C(OCC1(CO)C/C(C(O1)=O)=CCC(CC(C)C)CC(C)C)=O |
