Ajmaline

• CAT Number: I000043
• CAS Number: 4360-12-7
• Molecular Formula: C20H26N2O2
• Molecular Weight: 326.43
• Purity: ≥95%
• Target: Sodium Channel
• Solubility: 4.09 g/L in H2O
• Storage: 3 years -20C powder
• IUPAC Name: (1R,9R,10S,12R,13S,14R,16S,17S,18R)-13-ethyl-8-methyl-8,15-diazahexacyclo[14.2.1.01,9.02,7.010,15.012,17]nonadeca-2,4,6-triene-14,18-diol
• InChI: InChI=1S/C20H26N2O2/c1-3-10-11-8-14-17-20(12-6-4-5-7-13(12)21(17)2)9-15(16(11)18(20)23)22(14)19(10)24/h4-7,10-11,14-19,23-24H,3,8-9H2,1-2H3/t10-,11-,14-,15-,16-,17-,18+,19+,20+/m0/s1
• InChIKey: CJDRUOGAGYHKKD-RQBLFBSQSA-N
• SMILES: CC[C@H]1[C@@H]2C[C@H]3[C@H]4[C@@]5(C[C@@H]([C@H]2[C@H]5O)N3[C@@H]1O)C6=CC=CC=C6N4C

Ajmaline（Cat No.:I000043）is a naturally occurring alkaloid derived from the Rauvolfia plant species, commonly used in the treatment of certain heart arrhythmias, especially in cases of ventricular arrhythmias and supraventricular tachycardia. It functions as a sodium channel blocker, slowing the conduction of electrical impulses in the heart, which helps to restore normal rhythm. Ajmaline is often used as a diagnostic tool in assessing arrhythmias, particularly in patients with Brugada syndrome. It has been found effective in both oral and intravenous formulations, but care is needed due to potential side effects like hypotension and arrhythmias.