AK-IN-1

• CAT Number: I042628
• CAS Number: 378775-98-5
• Molecular Formula: C22H21N3O4
• Molecular Weight: 391.42
• Purity: ≥95%
• Synonyms: 2-[[5,6-bis(4-methoxyphenyl)furo[2,3-d]pyrimidin-4-yl]amino]ethanol
• InChI: InChI=1S/C22H21N3O4/c1-27-16-7-3-14(4-8-16)18-19-21(23-11-12-26)24-13-25-22(19)29-20(18)15-5-9-17(28-2)10-6-15/h3-10,13,26H,11-12H2,1-2H3,(H,23,24,25)
• InChIKey: ARBUGBBNEFAECO-UHFFFAOYSA-N
• SMILES: COC1=CC=C(C=C1)C2=C(OC3=NC=NC(=C23)NCCO)C4=CC=C(C=C4)OC

AK-IN-1（Cat No.:I042628）is a selective inhibitor targeting the Akt kinase, a crucial protein in the phosphoinositide 3-kinase (PI3K) signaling pathway. Akt plays a significant role in regulating cell survival, growth, metabolism, and angiogenesis. Dysregulation of Akt signaling is linked to various cancers, cardiovascular diseases, and metabolic disorders. AK-IN-1 works by blocking Akt activation, thereby disrupting these aberrant pathways. This inhibition has shown potential for inhibiting tumor growth, improving insulin sensitivity, and offering therapeutic strategies for conditions such as cancer and diabetes, where Akt-mediated signaling plays a central role in disease progression.