Akuammigine

• CAT Number: R044480
• CAS Number: 642-17-1
• Molecular Formula: C21H24N2O3
• Molecular Weight: 352.43
• Purity: ≥95%
• Target: Neuronal Signaling
• Storage: 3 years -20C powder
• IUPAC Name: methyl (1R,15S,16S,20S)-16-methyl-17-oxa-3,13-diazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4,6,8,18-pentaene-19-carboxylate
• InChI: InChI=1S/C21H24N2O3/c1-12-16-10-23-8-7-14-13-5-3-4-6-18(13)22-20(14)19(23)9-15(16)17(11-26-12)21(24)25-2/h3-6,11-12,15-16,19,22H,7-10H2,1-2H3/t12-,15-,16-,19+/m0/s1
• InChIKey: GRTOGORTSDXSFK-BMYCAMMWSA-N
• SMILES: CC1C2CN3CCC4=C(C3CC2C(=CO1)C(=O)OC)NC5=CC=CC=C45

Akuammigine(CAT: R044480) is an indole alkaloid primarily found in the seeds of Picralima nitida, a plant native to West Africa. It has been traditionally used in herbal medicine for its analgesic, anti-inflammatory, and antipyretic properties. Akuammigine is structurally similar to certain opioids, and it interacts with opioid receptors, particularly the μ-opioid and κ-opioid receptors, providing pain-relief effects. However, it is considered to have lower potency than conventional opioids. Research on akuammigine has explored its potential as an alternative to opioid medications, given its natural origin and reduced risk of dependence. This compound is also being investigated for its possible use in treating conditions such as inflammation, fever, and gastrointestinal disorders.