[Ala11,D-Leu15]-Orexin B(human)

• CAT Number: P000146
• CAS Number: 532932-99-3
• Molecular Formula: C120H206N44O35S
• Molecular Weight: 2857.26
• Purity: ≥95%

[Ala11,D-Leu15]-Orexin B(human) is a potent and selective orexin-2 receptor (OX2) agonist. [Ala11,D-Leu15]-Orexin B(human) shows a 400-fold selectivity for the OX2 (EC50=0.13 nM) over OX1 (52 nM)[1].

Reference

[1]. Asahi S, et al. Development of an orexin-2 receptor selective agonist, [Ala(11), D-Leu(15)]orexin-B. Bioorg Med Chem Lett. 2003;13(1):111-113.
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