For research use only. Not for therapeutic Use.
Aladorian (ARM036) is a benzothiazepine derivative, with anti-arrhythmia effect. Aladorian is used for the research of heart failure and catecholaminergic polymorphic ventricular tachycardia[1][2].
| Catalog Number | R036607 |
| CAS Number | 865433-00-7 |
| Synonyms | 2-(7-methoxy-3,5-dihydro-2H-1,4-benzothiazepin-4-yl)-2-oxoacetic acid |
| Molecular Formula | C12H13NO4S |
| Purity | ≥95% |
| InChI | InChI=1S/C12H13NO4S/c1-17-9-2-3-10-8(6-9)7-13(4-5-18-10)11(14)12(15)16/h2-3,6H,4-5,7H2,1H3,(H,15,16) |
| InChIKey | FPWBHFYYVSNIFZ-UHFFFAOYSA-N |
| SMILES | COC1=CC2=C(C=C1)SCCN(C2)C(=O)C(=O)O |
| Reference | [1]. Thevis M, et al. Analytical approaches for the detection of emerging therapeutics and non-approved drugs in human doping controls. J Pharm Biomed Anal. 2014 Dec;101:66-83. [2]. Luo M, et al. Mechanisms of altered Ca²⁺ handling in heart failure. Circ Res. 2013 Aug 30;113(6):690-708. |
