ALC-0315

• CAT Number: I021738
• CAS Number: 2036272-55-4
• Molecular Formula: C48H95NO5
• Molecular Weight: 766.29
• Purity: 98%
• Synonyms: ALC-0315; ALC 0315; ALC0315
• Target: Anti-infection
• Solubility: Chloroform (50mg/mL) and ethanol (100mg/mL)
• Appearance: Colorless to light yellow oily liquid
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 6-[6-(2-hexyldecanoyloxy)hexyl-(4-hydroxybutyl)amino]hexyl 2-hexyldecanoate
• InChI: InChI=1S/C48H95NO5/c1-5-9-13-17-19-27-37-45(35-25-15-11-7-3)47(51)53-43-33-23-21-29-39-49(41-31-32-42-50)40-30-22-24-34-44-54-48(52)46(36-26-16-12-8-4)38-28-20-18-14-10-6-2/h45-46,50H,5-44H2,1-4H3
• InChIKey: QGWBEETXHOVFQS-UHFFFAOYSA-N
• SMILES: CCCCCCCCC(CCCCCC)C(=O)OCCCCCCN(CCCCCCOC(=O)C(CCCCCC)CCCCCCCC)CCCCO

ALC-0315（Cat No.:I021738）is a lipid nanoparticle (LNP) formulation used primarily in mRNA-based vaccines and therapeutics. Composed of a cationic lipid, cholesterol, and polyethylene glycol (PEG)-lipid, it enables the encapsulation and delivery of mRNA into cells. ALC-0315 facilitates the safe and efficient transport of mRNA to target cells, aiding in the expression of therapeutic proteins or antigens. This LNP system has gained significant attention for its role in the success of mRNA vaccines, ensuring stability, reducing toxicity, and enhancing immune response for various diseases.