Ald-CH2-PEG4-Boc

• CAT Number: I015847
• CAS Number: 1415329-20-2
• Molecular Formula: C₁₅H₂₈O₇
• Molecular Weight: 320.38
• Purity: ≥95%
• Target: PROTAC Linkers

Ald-CH2-PEG4-Boc (CAT: I015847) is a compound that belongs to the class of pegylated derivatives. It consists of an aldehyde group (Ald) connected to a four-unit polyethylene glycol (PEG4) spacer and protected with a tert-butyloxycarbonyl (Boc) group. The aldehyde group can undergo various chemical reactions, including reductive amination or conjugation with amine-containing molecules. The PEG4 spacer provides water solubility and flexibility, making it useful for linking different molecules together. The Boc protecting group can be removed under specific conditions to expose the aldehyde functionality for further functionalization. Ald-CH2-PEG4-Boc serves as a versatile building block in organic synthesis and drug development applications.

Reference

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562