For research use only. Not for therapeutic Use.
ALDH1A2-IN-1（Cat No.:I044456）is a selective small-molecule inhibitor of aldehyde dehydrogenase 1A2 (ALDH1A2), an enzyme responsible for the oxidation of retinaldehyde to retinoic acid, a key regulator of gene expression in development and differentiation. By inhibiting ALDH1A2, this compound reduces retinoic acid production, thereby modulating retinoid signaling pathways implicated in cancer, fibrosis, and developmental disorders. ALDH1A2-IN-1 is particularly useful in studies of retinoid metabolism, stem cell differentiation, and tumor progression. It serves as a valuable pharmacological tool for exploring ALDH1A2’s role in disease and evaluating potential therapeutic strategies targeting retinoic acid biosynthesis.
| CAS Number | 2204229-64-9 |
| Synonyms | (3-ethoxythiophen-2-yl)-[4-(4-nitro-3-pyrrolidin-1-ylphenyl)piperazin-1-yl]methanone |
| Molecular Formula | C21H26N4O4S |
| Purity | ≥95% |
| IUPAC Name | (3-ethoxythiophen-2-yl)-[4-(4-nitro-3-pyrrolidin-1-ylphenyl)piperazin-1-yl]methanone |
| InChI | InChI=1S/C21H26N4O4S/c1-2-29-19-7-14-30-20(19)21(26)24-12-10-22(11-13-24)16-5-6-17(25(27)28)18(15-16)23-8-3-4-9-23/h5-7,14-15H,2-4,8-13H2,1H3 |
| InChIKey | LAYJOGOQGVGOCO-UHFFFAOYSA-N |
| SMILES | CCOC1=C(SC=C1)C(=O)N2CCN(CC2)C3=CC(=C(C=C3)[N+](=O)[O-])N4CCCC4 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
