ALDH1A3-IN-2

• CAT Number: I043712
• CAS Number: 886502-08-5
• Molecular Formula: C13H17NO
• Molecular Weight: 203.28
• Purity: ≥95%
• Synonyms: 3-methyl-4-piperidin-1-ylbenzaldehyde
• InChI: InChI=1S/C13H17NO/c1-11-9-12(10-15)5-6-13(11)14-7-3-2-4-8-14/h5-6,9-10H,2-4,7-8H2,1H3
• InChIKey: PFELXGCZCNQNEM-UHFFFAOYSA-N
• SMILES: CC1=C(C=CC(=C1)C=O)N2CCCCC2

ALDH1A3-IN-2 (Compound 15) is a potent inhibitor of ALDH1A3 with an IC50 of 1.29 μM. Aldehyde dehydrogenases (ALDHs) are overexpressed in various tumor types including prostate cancer. ALDH1A3-IN-2 has the potential for the research of cancer diseases[1].

Reference

[1]. Ibrahim AIM, et al. Expansion of the 4-(Diethylamino)benzaldehyde Scaffold to Explore the Impact on Aldehyde Dehydrogenase Activity and Antiproliferative Activity in Prostate Cancer. J Med Chem. 2022 Mar 10;65(5):3833-3848.
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