For research use only. Not for therapeutic Use.
Alectinib M4 metabolite(CAT: C000026) is a significant active metabolite derived from Alectinib, a medication used in the treatment of non-small-cell lung cancer. Alectinib is classified as an anaplastic lymphoma kinase (ALK) inhibitor, and its primary mechanism of action is blocking the activity of the ALK protein. ALK is implicated in the growth and progression of certain types of lung cancer.
| Catalog Number | C000026 |
| CAS Number | 1256585-04-2 |
| Synonyms | 9-Ethyl-6,11-dihydro-8-[4-[(2-hydroxyethyl)amino]-1-piperidinyl]-6,6-dimethyl-11-oxo-5H-benzo[b]carbazole-3-carbonitrile |
| Molecular Formula | C₂₈H₃₂N₄O₂ |
| Purity | ≥95% |
| Solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
| Appearance | Off-White to Pale Brown Solid |
| Storage | 4°C |
| Reference | Heinig, K., et al.: Bioanalysis, 8, 1465-79 (2016); Morcos, P.N., et al.: Xenobiotica, 47, 217-29 (2017); |
