For research use only. Not for therapeutic Use.
Alendronic acid (Cat.No:I015454), also known as alendronate, is a medication used to treat osteoporosis and Paget’s disease of bone. It works by inhibiting the activity of osteoclasts, the cells responsible for breaking down bone tissue. This results in increased bone density and strength. Alendronic acid is taken orally and is available in tablet or solution form.
| Catalog Number | I015454 |
| CAS Number | 66376-36-1 |
| Molecular Formula | C₄H₁₃NO₇P₂ |
| Purity | ≥95% |
| IUPAC Name | (4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid |
| InChI | InChI=1S/C4H13NO7P2/c5-3-1-2-4(6,13(7,8)9)14(10,11)12/h6H,1-3,5H2,(H2,7,8,9)(H2,10,11,12) |
| InChIKey | OGSPWJRAVKPPFI-UHFFFAOYSA-N |
| SMILES | C(CC(O)(P(=O)(O)O)P(=O)(O)O)CN |
| Reference | [1]. Teixeira S, et al. Alendronic Acid as Ionic Liquid: New Perspective on Osteosarcoma. Pharmaceutics. 2020 Mar 24;12(3). pii: E293.<br>[2]. Duckworth AD, et al. Effect of Alendronic Acid on Fracture Healing: A Multicenter Randomized Placebo-Controlled Trial. J Bone Miner Res. 2019 Jun;34(6):1025-1032. |
