Alirinetide

• CAT Number: I006988
• CAS Number: 725715-18-4
• Molecular Formula: C36H54N12O9
• Molecular Weight: 798.89
• Purity: ≥95%
• Synonyms: (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid
• InChI: InChI=1S/C36H54N12O9/c1-20(29(51)46-26(34(56)57)10-6-16-43-36(40)41)44-32(54)27(18-22-11-13-23(50)14-12-22)47-31(53)25(9-5-15-42-35(38)39)45-33(55)28(19-49)48-30(52)24(37)17-21-7-3-2-4-8-21/h2-4,7-8,11-14,20,24-28,49-50H,5-6,9-10,15-19,37H2,1H3,(H,44,54)(H,45,55)(H,46,51)(H,47,53)(H,48,52)(H,56,57)(H4,38,39,42)(H4,40,41,43)/t20-,24-,25-,26-,27-,28-/m0/s1
• InChIKey: WVPOPWDCSFQEBI-HJJAOGADSA-N
• SMILES: C[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)NC(=O)[C@H](CC1=CC=C(C=C1)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CO)NC(=O)[C@H](CC2=CC=CC=C2)N

Alirinetide（Cat No.:I006988）is a novel investigational peptide-based therapeutic designed for the treatment of inflammatory and autoimmune conditions. It works by targeting and modulating the immune system’s response, specifically inhibiting the activation of certain cytokines and immune cells that contribute to inflammation. By reducing excessive immune activity, Alirinetide aims to alleviate symptoms and improve disease outcomes in conditions such as rheumatoid arthritis and other inflammatory disorders. Still in clinical development, it holds promise as an alternative to conventional immunosuppressive therapies, offering a potentially safer and more effective treatment option for patients with chronic inflammatory diseases.