Aliskiren Hemifumarate

• CAT Number: A000605
• CAS Number: 173334-58-2
• Molecular Formula: C₃₀H₅₃N₃O₆ • ½C₄H₄O₄
• Molecular Weight: 609.79
• Purity: ≥95%
• Synonyms: (αS,γS,δS,zS)-δ-Amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-γ-hydroxy-4-methoxy-3-(3-methoxypropoxy)-α,z-bis(1-methylethyl)benzeneoctanamide Hemifumarate; CGP 60536; CGP60536B; Rasilez Hemifumarate; SPP 100; Tekturna Hemifumarate
• Target: Autophagy
• Solubility: >58.5mg/mL in DMSO
• Storage: 3 years -20C powder
• IUPAC Name: (2S,4S,5S,7S)-5-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-4-hydroxy-7-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-8-methyl-2-propan-2-ylnonanamide;(E)-but-2-enedioic acid
• InChI: InChI=1S/2C30H53N3O6.C4H4O4/c2*1-19(2)22(14-21-10-11-26(38-8)27(15-21)39-13-9-12-37-7)16-24(31)25(34)17-23(20(3)4)28(35)33-18-30(5,6)29(32)36;5-3(6)1-2-4(7)8/h2*10-11,15,19-20,22-25,34H,9,12-14,16-18,31H2,1-8H3,(H2,32,36)(H,33,35);1-2H,(H,5,6)(H,7,8)/b;;2-1+/t2*22-,23-,24-,25-;/m00./s1
• InChIKey: KLRSDBSKUSSCGU-KRQUFFFQSA-N
• SMILES: CC(C)[C@@H](CC1=CC(=C(C=C1)OC)OCCCOC)C[C@@H]([C@H](C[C@@H](C(C)C)C(=O)NCC(C)(C)C(=O)N)O)N.CC(C)[C@@H](CC1=CC(=C(C=C1)OC)OCCCOC)C[C@@H]([C@H](C[C@@H](C(C)C)C(=O)NCC(C)(C)C(=O)N)O)N.C(=C/C(=O)O)\C(=O)O

Aliskiren Hemifumarate（Cat No.:A000605）is a high-purity renin inhibitor used in advanced hypertension research. By targeting renin, an enzyme involved in the renin-angiotensin-aldosterone system, Aliskiren Hemifumarate effectively reduces blood pressure, making it valuable for studies in cardiovascular therapy development. Its stable formulation ensures accurate, reliable results in various pharmacological investigations. With a focus on renin inhibition, this compound is suitable for exploring new avenues in managing hypertension and related cardiovascular conditions, providing a foundation for innovative therapeutic strategies in drug research.