Allisartan isoproxil

• CAT Number: I001760
• CAS Number: 947331-05-7
• Molecular Formula: C27H29ClN6O5
• Molecular Weight: 553.01
• Purity: ≥95%
• Synonyms: propan-2-yloxycarbonyloxymethyl 2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylate
• InChI: InChI=1S/C27H29ClN6O5/c1-4-5-10-22-29-24(28)23(26(35)37-16-38-27(36)39-17(2)3)34(22)15-18-11-13-19(14-12-18)20-8-6-7-9-21(20)25-30-32-33-31-25/h6-9,11-14,17H,4-5,10,15-16H2,1-3H3,(H,30,31,32,33)
• InChIKey: XMHJQQAKXRUCHI-UHFFFAOYSA-N
• SMILES: CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)C(=O)OCOC(=O)OC(C)C)Cl

Allisartan isoproxil（Cat No.:I001760）is a prodrug of allisartan, a potent angiotensin II receptor blocker (ARB) used to manage hypertension and certain cardiovascular conditions. It works by selectively blocking the angiotensin II type 1 receptor, which helps lower blood pressure by relaxing blood vessels and reducing fluid retention. Allisartan isoproxil is converted into the active form, allisartan, after administration, allowing for more efficient delivery and longer-lasting effects. Ongoing studies are evaluating its efficacy and safety compared to other ARBs, with the potential to offer a well-tolerated alternative for patients with high blood pressure.