For research use only. Not for therapeutic Use.
Allomatrine ((+)-Allomatrine) is an alkaloid from the bark of Sophora japonica. Allomatrine has antinociceptive properties mediated mainly through the activation ofκ-opioid receptors[1][2].
Catalog Number | I015306 |
CAS Number | 641-39-4 |
Synonyms | (1R,2R,9S,17R)-7,13-diazatetracyclo[7.7.1.02,7.013,17]heptadecan-6-one |
Molecular Formula | C15H24N2O |
Purity | ≥95% |
InChI | InChI=1S/C15H24N2O/c18-14-7-1-6-13-12-5-3-9-16-8-2-4-11(15(12)16)10-17(13)14/h11-13,15H,1-10H2/t11-,12+,13+,15+/m0/s1 |
InChIKey | ZSBXGIUJOOQZMP-KYEXWDHISA-N |
SMILES | C1CC2C3CCCN4C3C(CCC4)CN2C(=O)C1 |
Reference | [1]. Long Pan, et al. Chemical Constituents of Alkaloids From the Bark of Sophora Japonica. Zhong Yao Cai. 2016 Sep;39(9):2027-9. [2]. Seiichi Kobashi , et al. Antinociceptive Effects of 1-acyl-4-dialkylaminopiperidine and 1-alkyl-4-dialkylaminopiperidine in Mice: Structure-Activity Relation Study of Matrine-Type Alkaloids. Biol Pharm Bull. 2002 Aug;25(8):1030-4. |