Almitrine Dimesylate

• CAT Number: I002228
• CAS Number: 29608-49-9
• Molecular Formula: C28H37F2N7O6S2
• Molecular Weight: 669.76
• Purity: ≥95%
• Synonyms: Vectarion; Almitrin; Almitrina; Almitrinum; Almitrine.;6-[4-[bis(4-fluorophenyl)methyl]piperazin-1-yl]-N,N/’-diprop-2-enyl-1,3,5-triazine-2,4-diamine
• Target: Potassium Channel
• Solubility: Soluble in DMSO, not in water
• Storage: Store at 0-8 °C
• IUPAC Name: 6-[4-[bis(4-fluorophenyl)methyl]piperazin-1-yl]-2-N,4-N-bis(prop-2-enyl)-1,3,5-triazine-2,4-diamine;methanesulfonic acid
• InChI: InChI=1S/C26H29F2N7.2CH4O3S/c1-3-13-29-24-31-25(30-14-4-2)33-26(32-24)35-17-15-34(16-18-35)23(19-5-9-21(27)10-6-19)20-7-11-22(28)12-8-20;2*1-5(2,3)4/h3-12,23H,1-2,13-18H2,(H2,29,30,31,32,33);2*1H3,(H,2,3,4)
• InChIKey: MRDBGMJEPGXQHJ-UHFFFAOYSA-N
• SMILES: CS(=O)(=O)O.CS(=O)(=O)O.C=CCNC1=NC(=NC(=N1)N2CCN(CC2)C(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F)NCC=C

Almitrine dimesylate（Cat No.:I002228）is a drug used primarily to treat respiratory disorders, particularly in patients with chronic obstructive pulmonary disease (COPD) and other conditions causing low blood oxygen levels. It works by stimulating peripheral chemoreceptors in the carotid body, enhancing the sensitivity to low oxygen levels, and increasing ventilation. This leads to improved oxygenation in the blood. Almitrine dimesylate is also studied for its potential benefits in conditions like pulmonary hypertension and acute respiratory failure. However, its use has been limited due to potential side effects such as arrhythmias and its impact on blood pressure.