For research use only. Not for therapeutic Use.
Alogliptin-d3（Cat No.:S000267） is a deuterated form of alogliptin, where three hydrogen atoms are replaced with deuterium, increasing its molecular stability and making it valuable as an internal standard in analytical methods like mass spectrometry and NMR spectroscopy. Alogliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor used primarily to treat type 2 diabetes by enhancing the body’s ability to regulate blood sugar levels. The incorporation of deuterium in alogliptin-d3 allows for more precise pharmacokinetic and metabolic studies, providing clearer insights into the drug’s absorption, distribution, metabolism, and excretion.
| Catalog Number | S000267 |
| CAS Number | 1133421-35-8 |
| Molecular Formula | C18H18D3N5O2 |
| Purity | ≥95% |
| IUPAC Name | 2-[[6-[(3R)-3-aminopiperidin-1-yl]-2,4-dioxo-3-(trideuteriomethyl)pyrimidin-1-yl]methyl]benzonitrile |
| InChI | InChI=1S/C18H21N5O2/c1-21-17(24)9-16(22-8-4-7-15(20)12-22)23(18(21)25)11-14-6-3-2-5-13(14)10-19/h2-3,5-6,9,15H,4,7-8,11-12,20H2,1H3/t15-/m1/s1/i1D3 |
| InChIKey | ZSBOMTDTBDDKMP-DDOHFVCQSA-N |
| SMILES | CN1C(=O)C=C(N(C1=O)CC2=CC=CC=C2C#N)N3CCCC(C3)N |
