Alosetron-d3 hydrochloride

• CAT Number: S000317
• CAS Number: 1189919-71-8
• Molecular Formula: C17H16D3ClN4O
• Molecular Weight: 333.83
• Purity: ≥95%
• IUPAC Name: 2-[(5-methyl-1H-imidazol-4-yl)methyl]-5-(trideuteriomethyl)-3,4-dihydropyrido[4,3-b]indol-1-one;hydrochloride
• InChI: InChI=1S/C17H18N4O.ClH/c1-11-13(19-10-18-11)9-21-8-7-15-16(17(21)22)12-5-3-4-6-14(12)20(15)2;/h3-6,10H,7-9H2,1-2H3,(H,18,19);1H/i2D3
• InChIKey: FNYQZOVOVDSGJH-MUTAZJQDSA-N
• SMILES: CC1=C(N=CN1)CN2CCC3=C(C2=O)C4=CC=CC=C4N3C.Cl

Alosetron-d3 hydrochloride（Cat No.:S000317） is a deuterated form of alosetron hydrochloride, where three hydrogen atoms are replaced with deuterium. Alosetron is a serotonin 5-HT3 antagonist used primarily to manage severe diarrhea-predominant irritable bowel syndrome (IBS) in women. The addition of deuterium enhances the molecule’s stability, enabling more precise pharmacokinetic and metabolic studies. These studies are crucial for understanding how alosetron is absorbed, metabolized, and excreted in the body, leading to better therapeutic management, optimized dosing strategies, and minimized side effects, thereby improving the quality of life for patients with IBS.