Alpha-Latrotoxin

• CAT Number: P000011
• CAS Number: 65988-34-3
• Molecular Formula: C34H48N2O9
• Purity: ≥95%
• Solubility: Aqueous buffers, pH range 6.5-8.5
• Storage: It can be stored at 4 °C in presence of sodium azide up to 0.5 mg/ml during one month without any loss of activity or protein aggregation. A small amount of the lyophilized product cannot be dissolved. Repeating thawings and freezings cau

Alpha-Latrotoxin(cas 65988-34-3) is a presynaptic neurotoxin, specific to mammals.


1119-amino acid protein,<!—-> from Latrodectus (mactans) tredecimguttatus spider venom glands.

In vertebrates

Reference

– Krasnoperov et al., J. Natural Toxins (1992). 1:17

– Grasso, Biochem. Biophys. (1976) Acta 439:406

– Frontali et al., J. Cell Biol. (1976). 68:462

– Kiyatkin et al., FEBS Letts. (1990). 270:127

– Valtorta et al., J. Cell Biol. (1988). 107:2717

– Meldolesi et al., PNAS, USA (1984). 81:620

– Tzeng et al., J. Neurochem. (1979). 33:263

– Petrenko et al., Nature (1991). 353:65