alpha-Thujone

• CAT Number: R072414
• CAS Number: 546-80-5
• PubChem Substance ID: 261491
• Molecular Formula: C10H16O
• Molecular Weight: 152.237
• Purity: ≥95%
• IUPAC Name: (1S,4R,5R)-4-methyl-1-propan-2-ylbicyclo[3.1.0]hexan-3-one
• InChI: InChI=1S/C10H16O/c1-6(2)10-4-8(10)7(3)9(11)5-10/h6-8H,4-5H2,1-3H3/t7-,8-,10+/m1/s1
• InChIKey: USMNOWBWPHYOEA-MRTMQBJTSA-N
• SMILES: CC1C2CC2(CC1=O)C(C)C

Alpha-thujone(CAT: R072414) is a naturally occurring monoterpene ketone found in various plants, including some species of the Artemisia genus. Its mode of action involves interacting with gamma-aminobutyric acid (GABA) receptors in the brain, resulting in inhibitory effects and potentially leading to neurological effects. Pharmacologically, alpha-thujone is not used as a therapeutic drug due to its neurotoxic properties. In the past, it was used in alcoholic beverages like absinthe, contributing to its reputation for psychoactive effects. However, excessive consumption of alpha-thujone can lead to adverse reactions, and its use in alcoholic beverages is now strictly regulated in many countries.