For research use only. Not for therapeutic Use.
ALPK1-IN-2（Cat No.:I043660）is a selective small molecule inhibitor targeting ALPK1 (Alpha-kinase 1), a protein involved in regulating immune responses and inflammation. ALPK1 plays a role in the activation of pro-inflammatory pathways, particularly in response to bacterial infections and tissue damage. By inhibiting ALPK1, ALPK1-IN-2 aims to reduce excessive inflammation and modulate immune system activity. Preclinical studies suggest that ALPK1-IN-2 could be effective in treating inflammatory diseases, such as rheumatoid arthritis, and in conditions where abnormal immune activation contributes to tissue damage or disease progression.
| CAS Number | 2765633-68-7 |
| Synonyms | 4-(3,6-diazabicyclo[3.1.1]heptan-3-yl)-2,6-difluoro-N-(4-methoxy-1,3-benzothiazol-2-yl)benzamide |
| Molecular Formula | C20H18F2N4O2S |
| Purity | ≥95% |
| IUPAC Name | 4-(3,6-diazabicyclo[3.1.1]heptan-3-yl)-2,6-difluoro-N-(4-methoxy-1,3-benzothiazol-2-yl)benzamide |
| InChI | InChI=1S/C20H18F2N4O2S/c1-28-15-3-2-4-16-18(15)24-20(29-16)25-19(27)17-13(21)6-12(7-14(17)22)26-8-10-5-11(9-26)23-10/h2-4,6-7,10-11,23H,5,8-9H2,1H3,(H,24,25,27) |
| InChIKey | SHSJEVPKHXWBHO-UHFFFAOYSA-N |
| SMILES | COC1=C2C(=CC=C1)SC(=N2)NC(=O)C3=C(C=C(C=C3F)N4CC5CC(C4)N5)F |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
