Alprenolol hydrochloride

• CAT Number: I001429
• CAS Number: 13707-88-5
• Molecular Formula: C15H23NO2.HCl
• Molecular Weight: 285.81
• Purity: ≥95%
• Synonyms: (S)-1-(2-allylphenoxy)-3-(isopropylamino)propan-2-ol hydrochloride
• Target: Adrenergic Receptor
• Solubility: DMSO ≥ 31 mg/mL
• Storage: Store at RT
• IUPAC Name: 1-(propan-2-ylamino)-3-(2-prop-2-enylphenoxy)propan-2-ol;hydrochloride
• InChI: InChI=1S/C15H23NO2.ClH/c1-4-7-13-8-5-6-9-15(13)18-11-14(17)10-16-12(2)3;/h4-6,8-9,12,14,16-17H,1,7,10-11H2,2-3H3;1H
• InChIKey: RRCPAXJDDNWJBI-UHFFFAOYSA-N
• SMILES: CC(C)NCC(COC1=CC=CC=C1CC=C)O.Cl

Alprenolol hydrochloride (Cat.No:I001429) is a beta-adrenergic receptor blocker used for the treatment of hypertension and angina pectoris. It works by blocking the action of adrenaline and noradrenaline on the beta receptors, which causes a decrease in heart rate and blood pressure. Alprenolol hydrochloride is typically administered orally and is rapidly absorbed by the gastrointestinal tract.

Reference

[1]. Schreiber R et al. Involvement of 5-HT1A receptors in the anxiolytic action of S 14671 in the pigeon conflict test. Pharmacol Biochem Behav. 1995 Jun-Jul;51(2-3):211-5.

[2]. Millan MJ et al. Novel benzodioxopiperazines acting as antagonists at postsynaptic 5-HT1A receptors and as agonists at 5-HT1A autoreceptors: a comparative pharmacological characterization with proposed 5-HT1A antagonists. J Pharmacol Exp Ther, 1994 Jan, 268(1):337-52.