For research use only. Not for therapeutic Use.
Alstonidine acetate trihydrate (Cat No.: I021851) is a hydrated salt form of alstonidine, an indole alkaloid derived from plants of the Alstonia genus. It exhibits various bioactivities, including antitumor, antimalarial, and antimicrobial properties. The acetate trihydrate form enhances its solubility and stability for research applications. Alstonidine is of interest in natural product and pharmacological studies due to its complex structure and potential therapeutic effects. It serves as a valuable compound in drug discovery focused on natural alkaloid-based treatments for infectious and chronic diseases.
| CAS Number | 25442-92-6 |
| Synonyms | Alstonidine acetate trihydrate, Alstonidine acetyl deriv trihydrate |
| Molecular Formula | C24H32N2O8 |
| Purity | 98% |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | methyl (2S,3S,4S)-3-(acetoxymethyl)-2-methyl-4-((9-methyl-9H-pyrido[3,4-b]indol-1-yl)methyl)-3,4-dihydro-2H-pyran-5-carboxylate trihydrate |
| InChI | InChI=1S/C24H26N2O5.3H2O/c1-14-19(12-31-15(2)27)18(20(13-30-14)24(28)29-4)11-21-23-17(9-10-25-21)16-7-5-6-8-22(16)26(23)3;;;/h5-10,13-14,18-19H,11-12H2,1-4H3;3*1H2/t14-,18-,19-;;;/m0.../s1 |
| InChIKey | MCGHEKJRLIEUIK-HDTQAHQWSA-N |
| SMILES | O=C(C1=CO[C@@H](C)[C@H](COC(C)=O)[C@@H]1CC2=NC=CC3=C2N(C)C4=C3C=CC=C4)OC.[H]O[H].[H]O[H].[H]O[H] |
| Reference | 1: BOAZ H, ELDERFIELD RC, SCHENKER E. Alstonia alkaloids. VII. The structure of alstonidine. J Am Pharm Assoc Am Pharm Assoc. 1957 Aug;46(8):510-2. PubMed PMID: 13491437. |
