For research use only. Not for therapeutic Use.
AM-5308 is a potent kinesin KIF18A inhibitor (WO2021211549A1, C13)[1].
| Catalog Number | I044028 |
| CAS Number | 2410796-89-1 |
| Synonyms | 2-(6-azaspiro[2.5]octan-6-yl)-4-(2-hydroxyethylsulfonylamino)-N-[6-[(2R)-2-methylmorpholin-4-yl]pyridin-2-yl]benzamide |
| Molecular Formula | C26H35N5O5S |
| Purity | ≥95% |
| InChI | InChI=1S/C26H35N5O5S/c1-19-18-31(13-15-36-19)24-4-2-3-23(27-24)28-25(33)21-6-5-20(29-37(34,35)16-14-32)17-22(21)30-11-9-26(7-8-26)10-12-30/h2-6,17,19,29,32H,7-16,18H2,1H3,(H,27,28,33)/t19-/m1/s1 |
| InChIKey | IUDCFCQNVQWCCI-LJQANCHMSA-N |
| SMILES | CC1CN(CCO1)C2=CC=CC(=N2)NC(=O)C3=C(C=C(C=C3)NS(=O)(=O)CCO)N4CCC5(CC5)CC4 |
| Reference | [1]. Marc Noel PAYTON, et al. Kif18a inhibitors for treatment of neoplastic diseases. WO2021211549A1. |
