AM1241

• CAT Number: I001845
• CAS Number: 444912-48-5
• Molecular Formula: C22H22IN3O3
• Molecular Weight: 503.33
• Purity: ≥95%
• Storage: 3 years-20°Cpowder
• SMILES: CN1CCCCC1CN2C=C(C3=CC=CC=C32)C(=O)C4=C(C=CC(=C4)[N+](=O)[O-])I

AM-1241 is a selective cannabinoid CB2 receptor agonist with Ki of 3.4 nM, exhibits 82-fold selectivity over CB1 receptor.

Reference

[1] Ibrahim MM, et al. Pro Natl Acad Sci USA, 2003, 100(18), 10529-10533.
[2] Yao BB, et al, Br J Pharmacol, 2006, 149(2), 14-154.
[3] Nackley AG, et al, Neuroscience, 2003, 119(3), 747-757.
[4] Malan TP Jr, et al, Pain, 2002, 93(3), 239-245.
[5] Shoemaker JL, et al, J Neurochem, 2007, 101(1), 87-98.