For research use only. Not for therapeutic Use.
AM6538(CAT: I021893) is a high-affinity, long-acting inverse agonist of the cannabinoid receptor type 1 (CB1), widely used in research on the endocannabinoid system. By selectively targeting CB1 receptors, AM6538 provides valuable insights into the regulation of appetite, pain, mood, and addiction-related behaviors. This compound is instrumental in studying the therapeutic potential of CB1 modulation in conditions such as obesity, substance use disorders, and neurodegenerative diseases. With its robust activity, high specificity, and stability, AM6538 is suitable for both in vitro and in vivo studies, supporting the advancement of cannabinoid receptor research and the development of novel therapeutic strategies.
| Catalog Number | I021893 |
| CAS Number | 1245626-00-9 |
| Synonyms | AM6538; AM-6538; AM 6538 |
| Molecular Formula | C26H25Cl2N5O4 |
| Purity | 98% |
| Target | Neuronal Signaling |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | 4-(4-(1-(3,4-Dichlorophenyl)-4-methyl-3-(piperidin-1-ylcarbamoyl)-1H-pyrazol-5-yl)phenyl)but-3-yn-1-yl nitrate |
| InChI | InChI=1S/C26H25Cl2N5O4/c1-18-24(26(34)30-31-14-4-2-5-15-31)29-32(21-12-13-22(27)23(28)17-21)25(18)20-10-8-19(9-11-20)7-3-6-16-37-33(35)36/h8-13,17H,2,4-6,14-16H2,1H3,(H,30,34) |
| InChIKey | IJMJQCCTQKNWHO-UHFFFAOYSA-N |
| SMILES | O=[N+]([O-])OCCC#CC1=CC=C(C2=C(C)C(C(NN3CCCCC3)=O)=NN2C4=CC=C(Cl)C(Cl)=C4)C=C1 |
