For research use only. Not for therapeutic Use.
Ambenonium Chloride(CAT: I001954) is a potent acetylcholinesterase inhibitor that prevents the breakdown of acetylcholine, thereby enhancing cholinergic neurotransmission at neuromuscular junctions. This mechanism increases muscle strength and improves neuromuscular function, making it valuable in neuromuscular research, particularly for studying myasthenia gravis and other neuromuscular disorders. By sustaining acetylcholine levels, Ambenonium Chloride helps researchers explore synaptic transmission, receptor sensitivity, and potential therapeutic approaches for managing muscle weakness and fatigue. Its role in modulating cholinergic signaling also aids in the development of treatments targeting neurodegenerative diseases and neuromuscular dysfunctions.
Catalog Number | I001954 |
CAS Number | 7648-98-8 |
Synonyms | Ambenonium chloride; Ambenonium dichloride; Ambenonii chloridum; Ambestigmin chloride; Mytelase; Misuran;2,2/’-(oxalylbis(azanediyl))bis(N-(2-chlorobenzyl)-N,N-diethylethan-1-aminium) chloride |
Molecular Formula | C28H42Cl2N4O2+2 |
Purity | ≥95% |
Target | cholinergic agonist |
Solubility | Soluble in DMSO, not in water |
Storage | 0 - 4°Cfor short term (days to weeks), or -20 °C for long term (months). |
IUPAC Name | (2-chlorophenyl)methyl-[2-[[2-[2-[(2-chlorophenyl)methyl-diethylazaniumyl]ethylamino]-2-oxoacetyl]amino]ethyl]-diethylazanium |
InChI | InChI=1S/C28H40Cl2N4O2/c1-5-33(6-2,21-23-13-9-11-15-25(23)29)19-17-31-27(35)28(36)32-18-20-34(7-3,8-4)22-24-14-10-12-16-26(24)30/h9-16H,5-8,17-22H2,1-4H3/p+2 |
InChIKey | OMHBPUNFVFNHJK-UHFFFAOYSA-P |
SMILES | CC[N+](CC)(CCNC(=O)C(=O)NCC[N+](CC)(CC)CC1=CC=CC=C1Cl)CC2=CC=CC=C2Cl |