Amelenodor

• CAT Number: I040081
• CAS Number: 2389235-01-0
• Molecular Formula: C24H21N3O3
• Molecular Weight: 399.44
• Purity: ≥95%
• Synonyms: 2-[3,5-bis[(6-methylpyridin-2-yl)oxy]phenoxy]-6-methylpyridine
• InChI: InChI=1S/C24H21N3O3/c1-16-7-4-10-22(25-16)28-19-13-20(29-23-11-5-8-17(2)26-23)15-21(14-19)30-24-12-6-9-18(3)27-24/h4-15H,1-3H3
• InChIKey: OPUQKVNCXCWRLR-UHFFFAOYSA-N
• SMILES: CC1=NC(=CC=C1)OC2=CC(=CC(=C2)OC3=CC=CC(=N3)C)OC4=CC=CC(=N4)C

Amelenodor (Cat No.: I040081) is a novel small-molecule compound with potential applications in neurological disease and inflammation research. It is designed to modulate key cell signaling pathways, influencing neuroprotection, immune response, and cellular homeostasis. With high bioavailability and selectivity, Amelenodor is suitable for in vitro and in vivo studies, supporting drug discovery and mechanistic research. Its unique structure enhances stability and efficacy, making it a valuable tool for developing innovative therapeutic strategies in neuroscience, immunology, and precision medicine.

Reference

[1]. Leber A, et al. Activation of NLRX1 by NX-13 Alleviates Inflammatory Bowel Disease through Immunometabolic Mechanisms in CD4+ T Cells. J Immunol. 2019;203(12):3407-3415.
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[2]. Leber A, et.al. Exploratory studies with NX-13: oral toxicity and pharmacokinetics in rodents of an orally active, gut-restricted first-in-class therapeutic for IBD that targets NLRX1 [published online ahead of print, 2019 Oct 25]. Drug Chem Toxicol. 2019;1-6.
[Content Brief]