For research use only. Not for therapeutic Use.
Amelubant（Cat No.:I001989）is a selective leukotriene A4 hydrolase (LTA4H) inhibitor, under investigation for its potential to treat inflammatory diseases such as chronic obstructive pulmonary disease (COPD) and asthma. By inhibiting LTA4H, Amelubant reduces the production of leukotriene B4 (LTB4), a pro-inflammatory mediator involved in the recruitment and activation of immune cells. This action helps to diminish inflammation and tissue damage associated with chronic respiratory conditions. Amelubant’s targeted approach offers promise in improving disease management and patient outcomes, making it a valuable candidate in respiratory and inflammatory disease research.
| Catalog Number | I001989 |
| CAS Number | 346735-24-8 |
| Synonyms | ethyl N-[4-[[3-[[4-[2-(4-hydroxyphenyl)propan-2-yl]phenoxy]methyl]phenyl]methoxy]benzenecarboximidoyl]carbamate |
| Molecular Formula | C33H34N2O5 |
| Purity | ≥95% |
| IUPAC Name | ethyl N-[4-[[3-[[4-[2-(4-hydroxyphenyl)propan-2-yl]phenoxy]methyl]phenyl]methoxy]benzenecarboximidoyl]carbamate |
| InChI | InChI=1S/C33H34N2O5/c1-4-38-32(37)35-31(34)25-8-16-29(17-9-25)39-21-23-6-5-7-24(20-23)22-40-30-18-12-27(13-19-30)33(2,3)26-10-14-28(36)15-11-26/h5-20,36H,4,21-22H2,1-3H3,(H2,34,35,37) |
| InChIKey | SBVYURPQULDJTI-UHFFFAOYSA-N |
| SMILES | CCOC(=O)NC(=N)C1=CC=C(C=C1)OCC2=CC(=CC=C2)COC3=CC=C(C=C3)C(C)(C)C4=CC=C(C=C4)O |
