Ametoctradin

• CAT Number: I021950
• CAS Number: 865318-97-4
• Molecular Formula: C15H25N5
• Molecular Weight: 275.4
• Purity: 98%
• Synonyms: Ametoctradin, BAS-650F, Initium
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: -20°C
• IUPAC Name: 5-Ethyl-6-octyl-(1,2,4)triazolo(1,5-a)pyrimidin-7-ylamine
• InChI: 1S/C15H25N5/c1-3-5-6-7-8-9-10-12-13(4-2)19-15-17-11-18-20(15)14(12)16/h11H,3-10,16H2,1-2H3
• InChIKey: GGKQIOFASHYUJZ-UHFFFAOYSA-N
• SMILES: CCCCCCCCc1c(N)n2ncnc2nc1CC

Ametoctradin（Cat No.:I021950）, is a pyrrole-based fungicide used in agriculture to combat fungal diseases. It acts by inhibiting mitochondrial respiration in fungal pathogens, disrupting their energy production and ultimately causing their demise. Ametoctradin exhibits broad-spectrum activity against various types of fungi, including oomycetes and ascomycetes. It is commonly applied as a foliar spray or seed treatment to protect crops such as fruits, vegetables, cereals, and ornamental plants. By controlling fungal infections, Ametoctradin helps promote healthier plant growth and enhance overall crop yields, contributing to sustainable agricultural practices.

Reference

1: Dreinert A, Wolf A, Mentzel T, Meunier B, Fehr M. The cytochrome bc(1) complex inhibitor Ametoctradin has an unusual binding mode. Biochim Biophys Acta Bioenerg. 2018 Aug;1859(8):567-576. doi: 10.1016/j.bbabio.2018.04.008. Epub 2018 Apr 25. PubMed PMID: 29704498.
2: Zhu X, Zhang M, Liu J, Ge J, Yang G. Correction to ametoctradin is a potent qo site inhibitor of the mitochondrial respiration complex III. J Agric Food Chem. 2015 Nov 18;63(45):10096. doi: 10.1021/acs.jafc.5b05259. Epub 2015 Nov 9. PubMed PMID: 26551250.
3: Fehr M, Wolf A, Stammler G. Binding of the respiratory chain inhibitor ametoctradin to the mitochondrial bc1 complex. Pest Manag Sci. 2016 Mar;72(3):591-602. doi: 10.1002/ps.4031. Epub 2015 May 20. PubMed PMID: 25914236.
4: Zhu X, Zhang M, Liu J, Ge J, Yang G. Ametoctradin is a potent Qo site inhibitor of the mitochondrial respiration complex III. J Agric Food Chem. 2015 Apr 8;63(13):3377-86. doi: 10.1021/acs.jafc.5b00228. Epub 2015 Mar 25. Erratum in: J Agric Food Chem. 2015 Nov 18;63(45):10096. PubMed PMID: 25784492.