For research use only. Not for therapeutic Use.
AMG 487 S-enantiomer is the S enantiomer of AMG 487. AMG 487 is an antagonist of the chemokine receptor CXCR3.
AMG 487 S-enantiomer (Compound 3.74) is the S enantiomer of AMG 487[1].
| Catalog Number | I003640 |
| CAS Number | 473720-30-8 |
| Synonyms | N-[(1S)-1-[3-(4-ethoxyphenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(pyridin-3-ylmethyl)-2-[4-(trifluoromethoxy)phenyl]acetamide |
| Molecular Formula | C32H28F3N5O4 |
| Purity | ≥95% |
| InChI | InChI=1S/C32H28F3N5O4/c1-3-43-25-14-10-24(11-15-25)40-30(38-29-27(31(40)42)7-5-17-37-29)21(2)39(20-23-6-4-16-36-19-23)28(41)18-22-8-12-26(13-9-22)44-32(33,34)35/h4-17,19,21H,3,18,20H2,1-2H3/t21-/m0/s1 |
| InChIKey | WQTKNBPCJKRYPA-NRFANRHFSA-N |
| SMILES | CCOC1=CC=C(C=C1)N2C(=O)C3=C(N=CC=C3)N=C2C(C)N(CC4=CN=CC=C4)C(=O)CC5=CC=C(C=C5)OC(F)(F)F |
| Reference | [1]. CXCR3 ANTAGONISTS. WIPO Patent Application WO/2002/083143 |
