For research use only. Not for therapeutic Use.
AMG-8562 is a TRPV1 modulator.
Catalog Number | I002124 |
CAS Number | 1041478-78-7 |
Synonyms | AMG-8562; AMG8562; AMG 8562; UNII-X2S52Z1DY9; X2S52Z1DY9; SCHEMBL14993014; SCHEMBL14993018;;2-Propenamide, N-((2R)-2,3-dihydro-2-hydroxy-1H-inden-4-yl)-3-(2-(1-piperidinyl)-4-(trifluoromethyl)phenyl)-, (2E)- |
Molecular Formula | C24H25F3N2O2 |
Purity | ≥95% |
Target | TRPV1 modulator |
Solubility | Soluble in DMSO, not in water |
Storage | 0 - 4°Cfor short term (days to weeks), or -20 °C for long term (months). |
IUPAC Name | (E)-N-[(2R)-2-hydroxy-2,3-dihydro-1H-inden-4-yl]-3-[2-piperidin-1-yl-4-(trifluoromethyl)phenyl]prop-2-enamide |
InChI | InChI=1S/C24H25F3N2O2/c25-24(26,27)18-9-7-16(22(14-18)29-11-2-1-3-12-29)8-10-23(31)28-21-6-4-5-17-13-19(30)15-20(17)21/h4-10,14,19,30H,1-3,11-13,15H2,(H,28,31)/b10-8+/t19-/m1/s1 |
InChIKey | HAZYXDWNLMGLIS-LHUXKHBRSA-N |
SMILES | C1CCN(CC1)C2=C(C=CC(=C2)C(F)(F)F)C=CC(=O)NC3=CC=CC4=C3CC(C4)O |