Amibegron

• CAT Number: I021974
• CAS Number: 121524-08-1
• Molecular Formula: C22H26ClNO4
• Molecular Weight: 403.91
• Purity: 98%
• Synonyms: Amibegron, SR 58611, SR58611, SR-58611
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: ethyl 2-[[(7S)-7-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]-5,6,7,8-tetrahydronaphthalen-2-yl]oxy]acetate
• InChI: InChI=1S/C22H26ClNO4/c1-2-27-22(26)14-28-20-9-7-15-6-8-19(11-17(15)12-20)24-13-21(25)16-4-3-5-18(23)10-16/h3-5,7,9-10,12,19,21,24-25H,2,6,8,11,13-14H2,1H3/t19-,21-/m0/s1
• InChIKey: RDJQCOBTKKAQAH-FPOVZHCZSA-N
• SMILES: CCOC(=O)COC1=CC2=C(CC[C@@H](C2)NC[C@@H](C3=CC(=CC=C3)Cl)O)C=C1

Amibegron(CAT: I021974) (also known as SR58611A) is a selective β3-adrenergic receptor agonist. By activating β3-adrenergic receptors, primarily found in adipose tissue, skeletal muscle, and the central nervous system, Amibegron modulates lipid metabolism, enhances energy expenditure, and influences neurotransmitter release. It has been studied for its anxiolytic and antidepressant effects due to its ability to regulate stress-related pathways without sedative side effects. Amibegron holds potential in neuropsychiatric research for treating anxiety disorders, depression, and metabolic conditions, offering a novel therapeutic approach by targeting the β3-adrenergic signaling pathway.