For research use only. Not for therapeutic Use.
<p style=/line-height:25px/>Amicarbazone(BAY-MKH3586; BAY314666) is a potent inhibitor of photosynthetic electron transport via binding to the Qb domain of photosystem II (PSII); herbicide with a broad spectrum of weed control.<br>IC50 value:<br>Target: PSII inhibitor<br>The phenotypic responses of sensitive plants exposed to amicarbazone include chlorosis, stunted growth, tissue necrosis, and death. Its efficacy as both a foliar- and root-applied herbicide suggests that absorption and translocation of this compound is very rapid. As a result, its efficacy is susceptible to the most common form of resistance to PSII inhibitors. Nonetheless, amicarbazone has a good selectivity profile and is a more potent herbicide than atrazine, which enables its use at lower rates than those of traditional photosynthetic inhibitors.</p>
| Catalog Number | I001146 |
| CAS Number | 129909-90-6 |
| Molecular Formula | C10H19N5O2 |
| Purity | ≥95% |
| Target | PSII inhibitor |
| Solubility | 10 mM in DMSO |
| Storage | Store at -20°C |
| InChI | InChI=1S/C21H23NO3/c1-21(2,3)16-7-4-15(5-8-16)6-11-20(23)22-17-9-10-18-19(14-17)25-13-12-24-18/h4-11,14H,12-13H2,1-3H3,(H,22,23)/b11-6+ |
| InChIKey | GZTFUVZVLYUPRG-IZZDOVSWSA-N |
| SMILES | CC(C)(C)c1ccc(cc1)/C=C/C(=O)Nc2ccc3c(c2)OCCO3 |
| Reference | </br>1:Dissipation kinetics and degradation mechanism of amicarbazone in soil revealed by a reliable LC-MS/MS method. Dong M, Han W, Ediage EN, Fan L, Tang H, Wang W, Han L, Zhao Z, Song W, Han Z.Environ Sci Pollut Res Int. 2015 Nov;22(22):17518-26. doi: 10.1007/s11356-015-4899-3. Epub 2015 Jul 4. PMID: 26139399 </br>2:Analysis of amicarbazone and its two metabolites in grains and soybeans by liquid chromatography with tandem mass spectrometry. Dong M, Nie D, Tang H, Rao Q, Qu M, Wang W, Han L, Song W, Han Z.J Sep Sci. 2015 Jul;38(13):2245-52. doi: 10.1002/jssc.201500265. Epub 2015 May 19. PMID: 25907799 </br>3:Physiological effects of temperature on turfgrass tolerance to amicarbazone. Yu J, McCullough PE, Grey T.Pest Manag Sci. 2015 Apr;71(4):571-8. doi: 10.1002/ps.3853. Epub 2014 Aug 13. PMID: 25045054 </br>4:Amicarbazone. Kaur M, Butcher RJ, Jasinski JP, Yathirajan HS, Siddaraju BP.Acta Crystallogr Sect E Struct Rep Online. 2013 Mar 28;69(Pt 4):o603. doi: 10.1107/S1600536813007782. Print 2013 Apr 1. PMID: 23634130 Free PMC Article |
