Amidopyrine

For research use only. Not for therapeutic Use.

  • CAT Number: A000220
  • CAS Number: 58-15-1
  • Molecular Formula: C13H17N3O
  • Molecular Weight: 231.29
  • Purity: ≥95%
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Aminophenazone, also known as aminopyrine, is a non-steroidal anti-inflammatory drugs used to treat pain and inflammation.


Catalog Number A000220
CAS Number 58-15-1
Synonyms

AMINOPYRINE; Amidopyrine; 4-Dimethylaminoantipyrine; Dipyrine; 58-15-1

Molecular Formula C13H17N3O
Purity ≥95%
Storage -20°C
InChI 1S/C13H17N3O/c1-10-12(14(2)3)13(17)16(15(10)4)11-8-6-5-7-9-11/h5-9H,1-4H3
InChIKey RMMXTBMQSGEXHJ-UHFFFAOYSA-N
SMILES CC1=C(C(=O)N(N1C)C2=CC=CC=C2)N(C)C
Reference

1: Roberts AG, Sjögren SE, Fomina N, Vu KT, Almutairi A, Halpert JR. NMR-derived
models of amidopyrine and its metabolites in complexes with rabbit cytochrome
P450 2B4 reveal a structural mechanism of sequential N-dealkylation.
Biochemistry. 2011 Mar 29;50(12):2123-34. doi: 10.1021/bi101797v. Epub 2011 Mar
4. PubMed PMID: 21375273; PubMed Central PMCID: PMC3163098.
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2: Petrenko AIu, Povolotskaia VA, Rosliakov AD, Libina VV, Cha&#301;ka LA.
[Comparative study of the effect of paracetamol, phenacetin and amidopyrine on
mitochondrial function in isolated rat hepatocytes]. Ukr Biokhim Zh (1978). 1997
May-Jun;69(3):72-6. Russian. PubMed PMID: 9505365.
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3: Korzhenevskaia MA, Mikheev VS. [Effect of immobilization of amidopyrine in
polyvinyl alcohol on mutagenicity of yeast]. Genetika. 1993 Apr;29(4):699-701.
Russian. PubMed PMID: 8354478.
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4: Kachurin AM, Kropachev EV, Iogannsen MG, Petrov AS. [Features of peroxidase
oxidation of amidopyrine and its analogs]. Biokhimiia. 1991 Oct;56(10):1768-78.
Russian. PubMed PMID: 1777517.
<br>

5: Noskov SM. [Megaloblastic pancytopenia in a female patient with rheumatoid
arthritis given methotrexate and amidopyrine simultaneously]. Ter Arkh.
1990;62(9):122-3. Russian. PubMed PMID: 2281394.

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6: Moroz BT, Ignatov IuD, Kalinin VI. [Thresholds of the electrical excitability
of the pulp in various groups of teeth and their changes under the influence of
analgin, amidopyrine and diazepam]. Stomatologiia (Mosk). 1989
Sep-Oct;68(5):30-2. Russian. PubMed PMID: 2588276.
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7: Adrianov NV, Dovgi&#301; AI, Kha&#301;lov PM. [The effect of phenobarbital and
amidopyrine on the rate of decomposition of isoforms of cytochrome P-450 in mouse
liver microsomes]. Biokhimiia. 1989 Jul;54(7):1120-5. Russian. PubMed PMID:
2804167.
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8: Savchenko MV, Ivanova LA. [Use of amidopyrine for assessing thiourea exposure
in industry]. Gig Tr Prof Zabol. 1988 Feb;(2):49-51. Russian. PubMed PMID:
3131193.
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9: Bai T, Jia JH. [Application of the derivative linear regression method of
multiwavelength data to the simultaneous determination of amidopyrine and
caffeine in compound amidopyrine and caffeine tablets]. Yao Xue Xue Bao.
1988;23(8):616-22. Chinese. PubMed PMID: 3254043.
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10: Tarakhovski&#301; ML, Za&#301;tseva NE, Mozalevski&#301; AF. [Individual characteristics and
effects of spasmolytics in relation to the oxidation phenotype of the marker
preparation amidopyrine in children with digestive and respiratory diseases].
Pediatriia. 1988;(4):43-7. Russian. PubMed PMID: 3205647.

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