Amikacin hydrate is broad spectrum aminoglycoside antibiotic derived from its counterpart kanamycin A.</br>Similar to other aminoglycosides, amikacin binds to the 30S ribosomal subunit resulting in an inability to read mRNA ultimately producing a faulty or nonexistent protein.
| Catalog Number | R022071 |
| CAS Number | 37517-28-5 |
| Synonyms | (S)-O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-D-glucopyranosyl-(1→4)]-N1-(4-amino-2-hydroxy-1-oxobutyl)-2-deoxy-D-streptamine; 1-N-[L-(-)-γ-Amino-α-hydroxybutyryl]kanamycin A; Amicacin; Amikacillin; Amikacin; Amikozit; Amukin; A |
| Molecular Formula | C22H43N5O13 |
| Purity | ≥95% |
| Target | Antibiotic |
| Solubility | >10.5mg/mL in DMSO |
| Storage | Store at -20C |
| InChIKey | LKCWBDHBTVXHDL-RMDFUYIESA-N |
| Reference | <p>Davis, Bernard D. /Mechanism of Bactericidal Action of Aminoglycosides./Microbiological Reviews 51.3 (1987): 341-50.</p></span></p> |
