Amiloride

For research use only. Not for therapeutic Use.

  • CAT Number: I002891
  • CAS Number: 2609-46-3
  • Molecular Formula: C6H8ClN7O
  • Molecular Weight: 229.63
  • Purity: ≥95%
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Amiloride(Cat No.:I002891)is a potassium-sparing diuretic used primarily to treat high blood pressure (hypertension) and edema (fluid retention) associated with conditions like heart failure, cirrhosis, and kidney disease. It works by inhibiting sodium channels in the kidneys, reducing sodium reabsorption and promoting water excretion, while retaining potassium. Unlike other diuretics, amiloride does not cause significant potassium loss, helping to prevent hypokalemia (low potassium levels). It is often used in combination with other diuretics to balance fluid levels without risking potassium depletion. Potential side effects include dizziness, nausea, and hyperkalemia (high potassium levels).


Catalog Number I002891
CAS Number 2609-46-3
Molecular Formula C6H8ClN7O
Purity ≥95%
Target Neuronal Signaling
Solubility 10 mM in DMSO
Storage Store at -20 ℃
IUPAC Name 3,5-diamino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide
InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15)
InChIKey XSDQTOBWRPYKKA-UHFFFAOYSA-N
SMILES C1(=C(N=C(C(=N1)Cl)N)N)C(=O)N=C(N)N

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