For research use only. Not for therapeutic Use.
Amiloride(Cat No.:I002891)is a potassium-sparing diuretic used primarily to treat high blood pressure (hypertension) and edema (fluid retention) associated with conditions like heart failure, cirrhosis, and kidney disease. It works by inhibiting sodium channels in the kidneys, reducing sodium reabsorption and promoting water excretion, while retaining potassium. Unlike other diuretics, amiloride does not cause significant potassium loss, helping to prevent hypokalemia (low potassium levels). It is often used in combination with other diuretics to balance fluid levels without risking potassium depletion. Potential side effects include dizziness, nausea, and hyperkalemia (high potassium levels).
Catalog Number | I002891 |
CAS Number | 2609-46-3 |
Molecular Formula | C6H8ClN7O |
Purity | ≥95% |
Target | Neuronal Signaling |
Solubility | 10 mM in DMSO |
Storage | Store at -20 ℃ |
IUPAC Name | 3,5-diamino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide |
InChI | InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) |
InChIKey | XSDQTOBWRPYKKA-UHFFFAOYSA-N |
SMILES | C1(=C(N=C(C(=N1)Cl)N)N)C(=O)N=C(N)N |