For research use only. Not for therapeutic Use.
Amino-PEG10-amine(CAT: I014071) is a polyethylene glycol (PEG) derivative containing a primary amine group at one end. The PEG spacer provides hydrophilicity and flexibility to the molecule, while the terminal primary amine group allows for conjugation with other molecules or surfaces. Amino-PEG10-amine is commonly used in bioconjugation and drug delivery applications, where the PEG spacer helps improve the solubility, biocompatibility, and stability of the conjugated molecules. Its versatile amine functionality enables the attachment of various ligands, drugs, or biomolecules for targeted delivery or other biomedical applications.
| Catalog Number | I014071 |
| CAS Number | 928292-69-7 |
| Synonyms | Amino-PEG10-amine;3,6,9,12,15,18,21,24,27,30-decaoxadotriacontane-1,32-diamine |
| Molecular Formula | C22H48N2O10 |
| Purity | ≥95% |
| Target | PROTAC Linkers |
| Solubility | Soluble in DMSO |
| InChI | InChI=1S/C22H48N2O10/c23-1-3-25-5-7-27-9-11-29-13-15-31-17-19-33-21-22-34-20-18-32-16-14-30-12-10-28-8-6-26-4-2-24/h1-24H2 |
| InChIKey | YMQALIUBVKNYIJ-UHFFFAOYSA-N |
| SMILES | NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN |
| Reference | </br>1: Pignatello R, Impallomeni G, Pistarà V, Cupri S, Graziano AC, Cardile V, Ballistreri A. New amphiphilic derivatives of poly(ethylene glycol) (PEG) as surface modifiers of colloidal drug carriers. III. Lipoamino acid conjugates with carboxy- and amino-PEG(5000) polymers. Mater Sci Eng C Mater Biol Appl. 2015 Jan;46:470-81. doi: 10.1016/j.msec.2014.10.054. Epub 2014 Oct 23. PubMed PMID: 25492012.</br>2: Rubio-Garcia J, Coppel Y, Lecante P, Mingotaud C, Chaudret B, Gauffre F, Kahn ML. One-step synthesis of metallic and metal oxide nanoparticles using amino-PEG oligomers as multi-purpose ligands: size and shape control, and quasi-universal solvent dispersibility. Chem Commun (Camb). 2011 Jan 21;47(3):988-90. doi: 10.1039/c0cc02615h. Epub 2010 Nov 26. PubMed PMID: 21113535.</br>3: Kitagawa F, Kubota K, Sueyoshi K, Otsuka K. One-step preparation of amino-PEG modified poly(methyl methacrylate) microchips for electrophoretic separation of biomolecules. J Pharm Biomed Anal. 2010 Dec 15;53(5):1272-7. doi: 10.1016/j.jpba.2010.07.008. Epub 2010 Aug 1. PubMed PMID: 20678876.</br>4: Yoshimoto K, Hoshino Y, Ishii T, Nagasaki Y. Binding enhancement of antigen-functionalized PEGylated gold nanoparticles onto antibody-immobilized surface by increasing the functionalized antigen using alpha-sulfanyl-omega-amino-PEG. Chem Commun (Camb). 2008 Nov 14;(42):5369-71. doi: 10.1039/b811818c. Epub 2008 Sep 16. PubMed PMID: 18985213.</br></br> |
