For research use only. Not for therapeutic Use.
Amino-PEG5-alcohol (Cat No.:I014107) is a compound consisting of a polyethylene glycol (PEG) chain with five ethylene glycol units, combined with an amino group and an alcohol group. It is commonly used as a linker or spacer molecule in various biomedical applications. The PEG chain provides water solubility and improved biocompatibility, while the amino and alcohol groups allow for versatile chemical modifications. Amino-PEG5-alcohol is utilized in drug delivery systems, surface modification of biomaterials, and protein conjugation, enabling the attachment of other molecules for targeted applications in the biomedical field.
| Catalog Number | I014107 |
| CAS Number | 34188-11-9 |
| Synonyms | Amino-PEG5-alcohol;14-amino-3,6,9,12-tetraoxatetradecan-1-ol |
| Molecular Formula | C10H23NO5 |
| Purity | ≥95% |
| Target | Antibody-drug Conjugate/ADC Related |
| Solubility | Soluble in DMSO |
| IUPAC Name | 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethanol |
| InChI | InChI=1S/C10H23NO5/c11-1-3-13-5-7-15-9-10-16-8-6-14-4-2-12/h12H,1-11H2 |
| InChIKey | DEOUHEFHTMMUCM-UHFFFAOYSA-N |
| SMILES | C(COCCOCCOCCOCCO)N |
| Reference | </br>1: Pignatello R, Impallomeni G, Pistarà V, Cupri S, Graziano AC, Cardile V, Ballistreri A. New amphiphilic derivatives of poly(ethylene glycol) (PEG) as surface modifiers of colloidal drug carriers. III. Lipoamino acid conjugates with carboxy- and amino-PEG(5000) polymers. Mater Sci Eng C Mater Biol Appl. 2015 Jan;46:470-81. doi: 10.1016/j.msec.2014.10.054. Epub 2014 Oct 23. PubMed PMID: 25492012.</br>2: Rubio-Garcia J, Coppel Y, Lecante P, Mingotaud C, Chaudret B, Gauffre F, Kahn ML. One-step synthesis of metallic and metal oxide nanoparticles using amino-PEG oligomers as multi-purpose ligands: size and shape control, and quasi-universal solvent dispersibility. Chem Commun (Camb). 2011 Jan 21;47(3):988-90. doi: 10.1039/c0cc02615h. Epub 2010 Nov 26. PubMed PMID: 21113535.</br>3: Kitagawa F, Kubota K, Sueyoshi K, Otsuka K. One-step preparation of amino-PEG modified poly(methyl methacrylate) microchips for electrophoretic separation of biomolecules. J Pharm Biomed Anal. 2010 Dec 15;53(5):1272-7. doi: 10.1016/j.jpba.2010.07.008. Epub 2010 Aug 1. PubMed PMID: 20678876.</br>4: Yoshimoto K, Hoshino Y, Ishii T, Nagasaki Y. Binding enhancement of antigen-functionalized PEGylated gold nanoparticles onto antibody-immobilized surface by increasing the functionalized antigen using alpha-sulfanyl-omega-amino-PEG. Chem Commun (Camb). 2008 Nov 14;(42):5369-71. doi: 10.1039/b811818c. Epub 2008 Sep 16. PubMed PMID: 18985213.</br></br> |
