Amino-PEG6-amine

For research use only. Not for therapeutic Use.

  • CAT Number: I014110
  • CAS Number: 76927-70-3
  • Molecular Formula: C14H32N2O6
  • Molecular Weight: 324.42
  • Purity: ≥95%
Inquiry Now

Amino-PEG6-amine (CAT: I014110) is a PEG-based compound featuring two amino groups, rendering it amenable to versatile chemical conjugation strategies. These amino groups exhibit reactivity towards various functional groups, including carboxylic acids, activated NHS esters, and carbonyls (such as ketones and aldehydes). This flexibility in reactivity makes Amino-PEG6-amine a valuable tool for the development of diverse conjugation approaches, including the construction of antibody-drug conjugates.


Catalog Number I014110
CAS Number 76927-70-3
Synonyms

Amino-PEG6-amine;3,6,9,12,15,18-hexaoxaicosane-1,20-diamine

Molecular Formula C14H32N2O6
Purity ≥95%
Target PROTAC Linkers
Solubility Soluble in DMSO
InChI InChI=1S/C14H32N2O6/c15-1-3-17-5-7-19-9-11-21-13-14-22-12-10-20-8-6-18-4-2-16/h1-16H2
InChIKey SEBZAAOSFDHURG-UHFFFAOYSA-N
SMILES NCCOCCOCCOCCOCCOCCOCCN
Reference

</br>1: Pignatello R, Impallomeni G, Pistarà V, Cupri S, Graziano AC, Cardile V, Ballistreri A. New amphiphilic derivatives of poly(ethylene glycol) (PEG) as surface modifiers of colloidal drug carriers. III. Lipoamino acid conjugates with carboxy- and amino-PEG(5000) polymers. Mater Sci Eng C Mater Biol Appl. 2015 Jan;46:470-81. doi: 10.1016/j.msec.2014.10.054. Epub 2014 Oct 23. PubMed PMID: 25492012.</br>2: Rubio-Garcia J, Coppel Y, Lecante P, Mingotaud C, Chaudret B, Gauffre F, Kahn ML. One-step synthesis of metallic and metal oxide nanoparticles using amino-PEG oligomers as multi-purpose ligands: size and shape control, and quasi-universal solvent dispersibility. Chem Commun (Camb). 2011 Jan 21;47(3):988-90. doi: 10.1039/c0cc02615h. Epub 2010 Nov 26. PubMed PMID: 21113535.</br>3: Kitagawa F, Kubota K, Sueyoshi K, Otsuka K. One-step preparation of amino-PEG modified poly(methyl methacrylate) microchips for electrophoretic separation of biomolecules. J Pharm Biomed Anal. 2010 Dec 15;53(5):1272-7. doi: 10.1016/j.jpba.2010.07.008. Epub 2010 Aug 1. PubMed PMID: 20678876.</br>4: Yoshimoto K, Hoshino Y, Ishii T, Nagasaki Y. Binding enhancement of antigen-functionalized PEGylated gold nanoparticles onto antibody-immobilized surface by increasing the functionalized antigen using alpha-sulfanyl-omega-amino-PEG. Chem Commun (Camb). 2008 Nov 14;(42):5369-71. doi: 10.1039/b811818c. Epub 2008 Sep 16. PubMed PMID: 18985213.</br></br>

Request a Quote