Amino-PEG6-t-butyl ester

• CAT Number: I014111
• CAS Number: 1286281-32-0
• Molecular Formula: C19H39NO8
• Molecular Weight: 409.52
• Purity: ≥95%
• Synonyms: Amino-PEG6-t-butyl ester;tert-butyl 1-amino-3,6,9,12,15,18-hexaoxahenicosan-21-oate
• Target: Antibody-drug Conjugate/ADC Related
• Solubility: Soluble in DMSO
• Storage: -20°C
• IUPAC Name: tert-butyl 3-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
• InChI: InChI=1S/C19H39NO8/c1-19(2,3)28-18(21)4-6-22-8-10-24-12-14-26-16-17-27-15-13-25-11-9-23-7-5-20/h4-17,20H2,1-3H3
• InChIKey: QGSFECNPSLZGGT-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCN

NH2-PEG6-Boc is a PEG-based PROTAC linker that falls under the PEG class. It serves as a crucial component in the synthesis of PROTAC molecules, which are designed for targeted protein degradation. NH2-PEG6-Boc consists of six units of PEG, providing flexibility and solubility to the resulting conjugates. Additionally, it can be employed as a non-cleavable ADC linker, enabling the construction of antibody-drug conjugates (ADCs) for targeted drug delivery applications. The versatility and compatibility of NH2-PEG6-Boc make it valuable in the development of novel therapeutics.

Reference

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