Aminoadipic acid-d3

• CAT Number: I045593
• CAS Number: 2483832-01-3
• Molecular Formula: C6H8D3NO4
• Molecular Weight: 164.17
• Purity: ≥95%
• Synonyms: 2-amino-2,5,5-trideuteriohexanedioic acid
• InChI: InChI=1S/C6H11NO4/c7-4(6(10)11)2-1-3-5(8)9/h4H,1-3,7H2,(H,8,9)(H,10,11)/i3D2,4D
• InChIKey: OYIFNHCXNCRBQI-FBYXXYQPSA-N
• SMILES: C(CC(C(=O)O)N)CC(=O)O

Aminoadipic acid-d3 is the deuterium labeled Aminoadipic acid. Aminoadipic acid is an intermediate in the metabolism of lysine and saccharopine.
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Reference

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
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