Aminopurvalanol A

• CAT Number: I010499
• CAS Number: 220792-57-4
• Molecular Formula: C₁₉H₂₆ClN₇O
• Molecular Weight: 403.91
• Purity: ≥95%
• Synonyms: Alternative Name: NG 97
• Target: Cyclin-Dependent Kinases
• Solubility: Soluble to 100 mM in DMSO
• Storage: Store at 4℃
• IUPAC Name: (2R)-2-[[6-(3-amino-5-chloroanilino)-9-propan-2-ylpurin-2-yl]amino]-3-methylbutan-1-ol
• InChI: InChI=1S/C19H26ClN7O/c1-10(2)15(8-28)24-19-25-17(23-14-6-12(20)5-13(21)7-14)16-18(26-19)27(9-22-16)11(3)4/h5-7,9-11,15,28H,8,21H2,1-4H3,(H2,23,24,25,26)/t15-/m0/s1
• InChIKey: RAMROQQYRRQPDL-HNNXBMFYSA-N
• SMILES: CC(C)[C@H](CO)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NC3=CC(=CC(=C3)N)Cl

Aminopurvalanol A（Cat No.:I010499）is a potent and selective inhibitor of cyclin-dependent kinases (CDKs), particularly CDK1 and CDK2, which are key regulators of the cell cycle. By inhibiting these kinases, Aminopurvalanol A disrupts the progression of the cell cycle, leading to cell growth arrest and apoptosis, especially in rapidly dividing cancer cells. It is widely used in cancer research to study cell cycle regulation and explore therapeutic strategies targeting CDK-mediated pathways. This compound is valuable for developing novel cancer therapies and investigating the molecular mechanisms of cell cycle control.